Found 23 matching trials
Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases PHASE2 Brain metastases are the most common brain tumors in adults. It is estimate...
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National Taiwan University Hospital
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A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline NA Whole brain radiotherapy (WBRT) has long been a practical and effective the...
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Chang Gung Memorial Hospital
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Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases PHASE2 RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells.
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UAB Comprehensive Cancer Center
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Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC NA WBRT (whole-brain radiation therapy) exhibits poor tumor control and decrea...
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Active Not Recruiting
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SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC PHASE3 This phase III trial compares the effect of stereotactic radiosurgery and w...
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Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer NA Based on evidence that radiation-induced damage to the hippocampus plays a ...
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Affiliated Hospital of Academy of Military Medical Sciences
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Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer PHASE3 The incidence of brain metastases (BM) in metastatic breast cancer is incre...
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SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases PHASE2 The goal of this phase II randomized trial is to determine if Stereotactic ...
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Multiple Locations
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Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device NA Hippocampal-avoidance whole brain radiation therapy (HA-WBRT) limits radiat...
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Washington University School of Medicine
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Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy PHASE2 This clinical trial aims to evaluate the efficacy of early intervention wit...
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Multiple Locations
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